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مقاله
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Abstract
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Title:
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The effect of topical avastin in the success rate of dacryocystorhinostomy (DCR)
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Author(s):
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Dr Ali Salehi--Dr Alireza Zandy--Dr Seyed Mohammad Ali Abtahi
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Presentation Type:
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Poster
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Subject:
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Ophthalmic Plastic and Reconstructive Surgery
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Others:
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Presenting Author:
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Name:
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Ali Salehi
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Affiliation :(optional)
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E mail:
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salehy109@yahoo.com
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Phone:
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03136261818
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Mobile:
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09131114368
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Purpose:
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Many factors are involved in the failure rate of DCR Surgery as the standard treatment of nasolacrimal duct obstraction.There is however a lot of evidence that bevacizumab(avastin) with less side effects, has the same anti fibrosis effects.In this study we evaluated the effect of this drug on the failure rate of DCR.
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Methods:
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60 Candidates for DCR were divided to 2 groups each one containing 30 patients.These 2 groupswere matched by sex and age.We used Avastin eye drop(5mg/ml)every 6 hours in one group for 2 weeks in addition to other post-op routine treatment.The patients were evaluated for failure of DCR 2 weeks and 3 months after surgery.
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Results:
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In the avastin group no patient showed DCR failure.In the other group 1 patient in 2 week and 2 patients in 3 months follow up showed failure.HOwever this diffference between 2 groups was not statistically significant and maybe due to small sample size.(p-0.327,fisher exact test).
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Conclusion:
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Avastin eye drop may lower the failure rate of DCR .This subject needs to be more evaluated in further studies.
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Attachment:
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