The aim of this study was to determine the distribution of corneal eccentricity in a normal population and to examine related factors.

This cross-sectional study was conducted in 2015. In this study, two villages were selected in Iran using multistage cluster sampling. Selected persons were invited to have a comprehensive eye examination. Examinations in each village were performed at a specific location under standard conditions. After testing for vision and refraction and conducting the slit lamp exam, e-value was measured with Pentacam.

Of the 3851 selected individuals, 3314 participated in the study. After applying the exclusion criteria, data from 2610 people was used in the analysis for this report. Mean e value was 0.53 (95% CI: 0.52 to 0.54); mean e value was not significantly different between males and females. Mean e value reduced with age from 0.60 in subjects aged 6-20 years to 0.47 in people older than 70 years. The hyperopic group of participants had significantly lower e value than myopic and emmetropic ones (p <0.001). The relationship of e value with age, gender, and other anterior segment variables and spherical equivalent was examined in a multiple linear regression model. In the final model, age, pupil diameter, anterior chamber volume, anterior chamber angle, and spherical equivalent refraction significantly correlated with e.

The results of this study can be used as a clinical reference for clinical issues.