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مقاله
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Abstract
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Title:
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Epidemiological and Histopathological Assessment of Corneal Dystrophies; a Decade of Experience at Farabi Eye Hospital
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Author(s):
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Zohreh Nozarian, ,Vahid Mehrtash, Fahimeh Asadi Amoli,Mohammad Soleimani, Seyed Ali Tabatabaei
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Presentation Type:
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Oral
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Subject:
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Cornea and Anterior Segment
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Others:
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Presenting Author:
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Name:
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Mohammad Soleimani
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Affiliation :(optional)
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Farabi Eye Hospital
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E mail:
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soleimani_md@yahoo.com
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Phone:
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88647168
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Mobile:
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09121096496
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Purpose:
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To carry out an epidemiological assessment of corneal dystrophies in Iranian patients via histopathological tools and determine the frequency of the different subtypes.
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Methods:
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In a retrospective effort, pathological files of patients who had corneal transplantation between the years 2002 and 2014 at Farabi Eye Hospital in Tehran, Iran were examined. Pathology samples dubbed with the diagnosis of corneal dystrophy were of interest. In addition, specific stains such as Masson’s trichrome, Alcian Blue and Congo Red ,…were used. For proper classification of various corneal dystrophies, the IC3D classification of corneal dystrophies-edition 2 was implemented.
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Results:
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Of the 5867 cornea samples retrieved from corneal transplant surgery, 239(4.07%) belonged to patients with corneal dystrophy (males=120[50.2%]; females=119[49.8%]). The greatest quantity of them (n=57; 23.8%) aged between 20 and 29 years. Macular corneal dystrophy was the most frequent corneal dystrophy subtype (n=117; 49%). Other types such as lattice corneal dystrophy (n=9; 3.8%), Granular corneal dystrophy type 2 (Avellino CD) (n=3; 1.3%) and Schnyder corneal dystrophy (n=2; 0.8%) were also detected.
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Conclusion:
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Macular corneal dystrophy is the most common corneal dystrophy subtype witnessed in Iranian patients going through corneal transplant surgery. Use of special stains in histopathology can avoid missing the diagnosis of particular corneal dystrophies such as Granular corneal dystrophy type 2.
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Attachment:
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