|
مقاله
|
Abstract
|
|
|
Title:
|
Distribution of Corneal Thickness and its Determinants in 6-12 Year-Old Children in an Iranian General Population
|
Author(s):
|
Hassan Hashemi MD, Raheleh Moravej MSc, Mohammad Saatchi MSc, Mehdi Khabazkhoob PhD, Akbar Fotouhi MD, PhD, Abbasali Yekta PhD, Mohammad Hassan Emamian MD, PhD
|
Presentation Type:
|
Oral
|
Subject:
|
Cornea and Anterior Segment
|
Others:
|
|
Presenting Author:
|
|
Name:
|
Raheleh Moravvej
|
Affiliation :(optional)
|
Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran
|
E mail:
|
baranrmom80@yahoo.com
|
Phone:
|
02165142147
|
Mobile:
|
09126949199
|
|
|
Purpose:
|
To determine the central corneal thickness (CCT), apex thickness, and paracentral thickness and their determinants in children aged 6-12 years.
|
Methods:
|
The present study was a part of the phase 1 of Shahroud School Children Eye Cohort Study. Cluster sampling with unequal cluster was done in urban areas while all children were invited to participate in the study in rural areas. The Pentacam HR (Oculus Inc., Lynnwood, WA) was used for measurements. CCT was measured within the central 3 mm zone of the cornea while the corneal thickness at 3 mm further from the center was considered the paracentral thickness.
|
Results:
|
Of 6624 students who were selected, 5620 participated in the study (response rate: 84.8%). The mean CCT and apex thickness was 556.31±34.24 and 557.47±34.33 micron, respectively. Moreover, the mean paracentral thickness was 657.79±39.84 micron in the superior, 633.05±40.17 micron in the inferior, 640.75±40.05 micron in the nasal, and 617.07±37.17 micron in the temporal region. Evaluation of the relationship between CCT and studied variables using a multiple regression model showed that CCT increased by 0.16 micron with every 1 mm increase in the anterior chamber volume(P-Value=<0.001) and decreased by 10.69 micron with every 1 mm increase in anterior chamber depth
(P-Value=<0.001). Moreover, CCT decreased by 5.99 micron with every 1 mm increase in the corneal curvature (P-Value=0.001) and increased by 8.81 micron with every 1 mm increase in the corneal volume (P-Value=0.001). Age, sex, and residence place were also found to be associated with CCT in the final model.
|
Conclusion:
|
The central cornea is thicker in Iranian children as compared to other races and is significantly associated by age, sex, residence place, and biometric characteristics like anterior chamber volume and depth, corneal curvature, and corneal volume.
Keywords: Central Corneal Thickness, Children, General Population, Iran
|
Attachment:
|
|
|
|